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med's go on Instagram: "Membranous nephropathy presents with nephrotic syndrome and is characterized on electron microscopy by subepithelial immune complex deposits, which create the classic “spike and dome” appearance due to GBM projections forming between immune deposits. It is most commonly caused by autoantibodies against the PLA2R receptor on podocytes (primary form), but can also be secondary to malignancy, hepatitis B, SLE, or drugs. Complement activation (C5b-9) leads to podocyte injury
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med's go on Instagram: "Membranous nephropathy presents with nephrotic syndrome and is characterized on electron microscopy by subepithelial immune complex deposits, which create the classic “spike and dome” appearance due to GBM projections forming between immune deposits. It is most commonly caused by autoantibodies against the PLA2R receptor on podocytes (primary form), but can also be secondary to malignancy, hepatitis B, SLE, or drugs. Complement activation (C5b-9) leads to podocyte injury
已浏览 4775 次2 个月之前
Instagrammedsgoscience
Medical Exam MCQs on Instagram: "Explanation:⤵️ *Correct Answer is A (Membranous nephropathy) 🔷A. Membranous nephropathy: Spike and dome due to subepithelial immune deposits on EM. 🔷B. Minimal Change Disease: EM shows foot process effacement, not spikes. 🔷C. Amyloidosis: Shows amyloid deposits; Congo red positive, not spike-and-dome. 🔷D. Post-streptoccocal Glomerulonephritis: Shows subepithelial humps, not spike-and-dome. #usmle #medicine #neetpg #medico #medical #medicalschool #medicalstude
0:05
Medical Exam MCQs on Instagram: "Explanation:⤵️ *Correct Answer is A (Membranous nephropathy) 🔷A. Membranous nephropathy: Spike and dome due to subepithelial immune deposits on EM. 🔷B. Minimal Change Disease: EM shows foot process effacement, not spikes. 🔷C. Amyloidosis: Shows amyloid deposits; Congo red positive, not spike-and-dome. 🔷D. Post-streptoccocal Glomerulonephritis: Shows subepithelial humps, not spike-and-dome. #usmle #medicine #neetpg #medico #medical #medicalschool #medicalstude
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Instagrammedexam.mcqs
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