1. High platelets, >450k, unexplained. Need to evaluate for primary thrombocytosis 2. High red cells. Hemoglobin>16g/dL, unexplained. Evaluate for polycythemia vera 3. High white blood cell count, unexplained. Evaluate for leukemia 4. Tear drop or nucleated red cells on the CBC differential. Evaluate for myelofibrosis
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1. High platelets, >450k, unexplained. Need to evaluate for …
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Do Red Blood Cells have Nucleus and Mitochondria?
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Replying to @Dr. Reese Jitters MD In a peripheral blood smear, a nucleated red blood cell (NRBC) appears distinct due to its nucleus, which is not present in mature red blood cells (RBCs). The key histological features include: \t1.\tNucleus: The nucleus of an NRBC is typically round or slightly oval and can be centrally or eccentrically located. It stains darkly with hematoxylin (basophilic), appearing dark purple to black. \t2.\tCytoplasm: The cytoplasm of NRBCs is more basophilic (blue) compa
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Replying to @Dr. Reese Jitters MD In a peripheral blood smear, a nuc…
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• All blood cells originate from hematopoietic stem cells in the bone marrow — a very common NCLEX concept. • Red Blood Cells (RBCs) contain hemoglobin for oxygen transport; lifespan 90–120 days. Low oxygen levels stimulate kidneys to release erythropoietin (EPO) → increases RBC production. • Neutrophils (55–70%) are the first line of defense in acute bacterial infection; lifespan 6–10 hours in circulation, 1–2 days in tissues. • Lymphocytes (T & B cells) mediate cell-mediated and humoral immuni
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Rose Apple on Instagram: "💐When Nucleated Red Blood Cells (NRBCs) are observed on a blood smear 💐 👉Polychromasia should always be looked for, as both findings are commonly associated with bone marrow response to increased red blood cell production, such as in anemia due to blood loss or hemolysis. 💐 Relationship between NRBC and Polychromasia💐 🔸NRBC → Seen when the bone marrow is highly stimulated and releases immature red blood cells that still contain a nucleus. 🔸Polychromasia → Reflect
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Rose Apple on Instagram: "💐When Nucleated Red Blood Cells (NRBC…
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