Every rare disease tells a story. Understanding how one unfolds — how it develops and evolves — is often the first step toward treating it. A small genetic error, a malfunctioning cell or a breakdown in a biological process can set disease in motion. But for many rare conditions, the course of progression remains unwritten. A groundbreaking natural history study led by researchers at Mayo Clinic's Center for Individualized Medicine and Department of Clinical Genomics aims to change that, advanci

Two patients living with chronic pain share how Mayo Clinic’s Pain Rehabilitation Program in Rochester, Minnesota, helped them rediscover control, confidence and joy in everyday life. Their stories highlight the power of evidence-based, team-led care to support healing — physically and emotionally. Virtual and in-person assessments are available in Minnesota, Florida and Arizona. Learn more: https://mayocl.in/3IeGCOE | Mayo Clinic

Watch Payton’s story and see how the Mayo Clinic Comprehensive Cancer Center helped her thrive. | Mayo Clinic