Sign up for our NewslettersOriginal storyThe Greenville County Sheriff's Office is actively searching for a man with medical ...

Two people are dead after two boats collided at Lake Greenwood Sunday morning. The South Carolina Department of Natural ...

Parts of the Upstate could see scattered showers and some gusty winds as Tropical Storm Chantel moves across the area.

Syracuse has been banking on a Missouri company with a 50-year, national track record to turn rows and rows of old, ...

The parents were convicted of exposing the infant to extreme heat and cold and witholding needed nourishment, which caused ...

For over a century, the Better Business Bureau of Upstate New York has been a trusted resource for both businesses and ...

Two other Upstate waterways, one in Western New York and one in the Adirondacks, also made the list of the nation's best ...

Two youth baseball coaches have been fired after they were filmed stripping naked and streaking at an upstate New York ...

Rochester's Upstate Interiors Academy trains diverse talent for commercial construction jobs, blending trade skills with soft ...

The Senate’s version of the “big, beautiful bill,” passed on Tuesday, includes a $6,000 tax deduction for Americans 65 or ...

Pack a cooler and your appetite for a tasty Upstate New York road trip adventure. In Buffalo, check out seven iconic food ...

Upstate Medical University is holding a groundbreaking ceremony for a new, state-of-the-art laboratory called the Upstate ...