Land is a finite resource, facing huge demands from a growing population that clamors for living space and food. Farming, meanwhile, is beset by soil degradation, water shortages, plummeting ...

Edited by Jiayang Li, Institute of Genetics and Developmental Biology Chinese Academy of Sciences, Beijing, China; received June 4, 2024; accepted January 24, 2025 ...

Edited by Joshua Combes, University of Colorado, Boulder, CO; received September 9, 2023; accepted February 10, 2024, by Editorial Board Member Bernard F. Schutz ...

Front Matter delves into the stories of science. News Features cover research trends in depth, Opinion pieces advance the debate on topics in science and science policy, Inner Workings explore cutting ...

Contributed by J. Wade Harper; received September 23, 2024; accepted October 30, 2024; reviewed by Pietro V. De Camilli and Michael Lazarou This contribution is part of the special series of Inaugural ...

Healthy brain function requires a delicate balance of neural excitation (E) and inhibition (I). In animals, this balance—the E/I ratio—is known to decrease with the maturation of inhibitory circuitry ...

Active fluids, such as bacterial suspensions and flowing tissues, often exhibit orientational order disrupted by topological defects. Much is understood about how internal driving powers ...

The generation of fusion kinases through gene rearrangement represents a primary mechanism of rearranged during transfection (RET) oncogenic conversion. The change of location, increased expression, ...

We present a method to recapitulate endochondral bone formation, the process through which long bones develop and grow, in cell culture. Our method begins with induced pluripotent stem cells (iPSCs) ...

In contrast to most crops, Vitis vinifera benefited little from classical breeding due to their heterozygosis. Strikingly, the main cultivated grape varieties that we see today have remained the same ...

Understanding the nature of glasses are one of the most interesting kernels in condensed matter physics. Glassy materials usually exhibit different types of relaxation modes, which are coupled with ...

Clinical studies have long suggested a link between type 2 diabetes (T2D) and Alzheimer’s disease (AD): T2D patients have higher rates of AD and exhibit more rapid disease progression, whereas AD ...