Stabilization of microtubule plus end-directed kinesin CENP-E at the metaphase kinetochores is important for chromosome alignment, but its mechanism remains unclear. Here, we show that CKAP5, a ...

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Brian's research focuses intersections between circadian rhythm and cancer. He utilizes cell line and mouse models of MYC-driven lung cancer to focus on how amplified MYC and metabolic stress disrupt ...

Amplified by social media, the overwhelmingly positive balance between population benefit and individual damage is forgotten. This has been the case for Covid vaccinations, where politics and health ...

Selective autophagy ensures the targeted degradation of damaged or surplus cellular components, including organelles, thereby ...

DnaK/DnaJ or Trigger factor and find that chaperone dependence during primary biogenesis in vivo does not track with ...

Peroxisomes are the cellular location of many antioxidants and are themselves significant producers of reactive oxygen species. In this report we demonstrate the induction of peroxisome biogenesis ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Atherosclerosis is characterized by the ...

Because plants require sunlight for photosynthesis they are inevitably exposed to ultraviolet light, including that in the wavelength range of 280–320 nm (ultraviolet‐B, UV‐B). UV‐B light is ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. ABCB1 is a broad-spectrum efflux pump central ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. In the pistil of flowering plants, each ovule ...