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Plants produce a wide diversity of compounds. Broadly, these are separated into primary metabolites, which are necessary for ...
Chronic kidney disease (CKD) is typically associated with severe fibrosis, the exact pathogenesis of which remains unclear.
Facundo D. Batista (Chief Editor) Facundo is the Phillip T. and Susan M. Ragon Professor of Microbiology and Immunology at Harvard Medical School, and Associate Director of the Ragon Institute of MGH, ...
N6-methyladenosine (m 6 A) exerts many of its regulatory effects on eukaryotic mRNAs by recruiting cytoplasmic YT521-B homology-domain family (YTHDF) proteins. Here, we show that in Arabidopsis ...
Prostate cancer (PCa) is the second most frequently occurring cancer and the fifth leading cause of cancer mortality among men worldwide in 2022 (Bray et al, 2024). Androgen receptor (AR) is ...
EMBO Press publishes five scientific journals: The EMBO Journal - Submit here The EMBO Journal has been EMBO's flagship publication for 40 years. With a scope that spans all areas of molecular biology ...
Rheumatoid arthritis (RA) is associated with heart and lung dysfunction. Current therapies fail to attenuate such complications. Here, we identify formyl-peptide receptor type 2 (FPR2) as a ...
Spatial metabolomics is transforming our understanding of microbial systems by uncovering the localized molecular dynamics ...
Fungal infections and autoimmunity share a complex, bidirectional relationship that significantly impacts patient outcomes. Emerging evidence highlights how fungal pathogens contribute to autoimmune ...
Neural stem cell (NSC) function in mammalian brains declines during aging, but the molecular mechanisms involved remain ill-defined. Here, integrated multi-omics reveals continuous alterations of ...
Chloride (Cl −) ions cause major damage to crops in saline soils. Understanding the key factors that influence Cl − uptake and translocation will aid the breeding of more salt-tolerant crops. Here, ...
Our study shows that TP53 mutations in AML cells lead to increased resistance to CAR T-cells in vitro. CAR T-cells co-incubated with target TP53 -mutant AML blasts exhibited decreased proliferation ...