After six months of treatment, medicines called 'biologics' seem to work best to clear raised patches of psoriasis on the skin. Longer studies are needed to assess the benefits and potential unwanted ...

What are the benefits and risks of natalizumab (NTZ) in people with multiple sclerosis (MS)?

There is limited evidence to support the use of tumor necrosis factor-alpha antagonists (anti-TNF) therapy for induction of remission in children with Crohn's disease. • More well-designed studies are ...

Improvement in IIM activity, as measured by the International Myositis Assessment and Clinical Studies Group (IMACS) definitions of improvement (DOI), may be more likely with abatacept treatment ...

Due to a lack of robust evidence, we could not determine the benefits and unwanted effects of hospital networks (organised trauma systems) or individual hospitals (designated trauma centres) that are ...

We found nine studies involving a total of 689 women with stress urinary incontinence. Nine studies compared vaginal lasers to either sham or lubricant, and one study compared vaginal lasers to ...

- Corticosteroids may decrease transient inflammatory reaction events associated with antibiotic treatment of leptospirosis infection, although the certainty of this evidence is very uncertain.

Transcranial laser therapy (low-level light therapy applied to the head) does not reduce the number of people who die or have moderate to severe disability at 90 days after ischaemic stroke (where ...

Topical silver treatments and silver dressings are increasingly used for the local treatment of contaminated or infected wounds, however, there is a lack of clarity regarding the evidence for their ...

Five trials compared interventions for maintaining soft tissue health around implants and a further six trials compared interventions to recover soft tissue health where there was evidence of ...

Dysmenorrhoea is a common gynaecological problem consisting of painful cramps accompanying menstruation, which in the absence of any underlying abnormality is known as primary dysmenorrhoea. Research ...

Cochrane Interactive Learning is our comprehensive course on how to conduct a systematic review. Equip yourself, or your staff and students, with the skills to conduct systematic reviews through ...