How is the eLife Model driving change in research? We explore some key milestones and accomplishments of the first two years ...

In the bacterium M. smegmatis, an enzyme called MftG allows the the cofactor mycofactocin to transfers electrons released during ethanol metabolism to the electron transport chain.

Acetylcholine in the prefrontal cortex modulates the impact of surprising outcomes on learning and decision-making.

A combination of methods, including a new method for tagging genes, demonstrates that the chemosensory co-receptors of Drosophila melanogaster (Orco, IR8a, IR25a, IR76b) are expressed widely and ...

Many animals exhibit an astonishing ability to form groups of large numbers of individuals. The dynamic properties of such groups have been the subject of intensive investigation. The actual grouping ...

Ancient DNA research in the past decade has revealed that European population structure changed dramatically in the prehistoric period (14,000–3000 years before present, YBP), reflecting the ...

Clarifying gene expression in narrowly defined neuronal populations can provide insight into cellular identity, computation, and functionality. Here, we used next-generation RNA sequencing (RNA-seq) ...

The findings provided by Mohibi et al. are important to the field of lipid metabolism and cancer and provide insight for an in vivo role of FDX1. The evidence is solid, utilizing multiple modalities ...

The spiking activity of populations of cortical neurons is well described by the dynamics of a small number of population-wide covariance patterns, whose activation we refer to as ‘latent dynamics’.

Cancer cells exist in a complex ecosystem with numerous other cell types in the tumor microenvironment (TME). The composition of this tumor/TME ecosystem will vary at each anatomic site and affects ...

Transmissible tumors in Hydra can manipulate host phenotype by inducing the growth of supernumerary tentacles, enhancing host foraging efficiency and promoting tumor vertical transmission, akin to ...

Internal ribosome entry sites (IRESs) are important RNA-based translation initiation signals, critical for infection by many pathogenic viruses. The hepatitis C virus (HCV) IRES is the prototype for ...