Perianal Paget’s disease (PPD) is a rare condition which is often associated with underlying malignancy. To definitively rule ...

Patients with inoperable hepatobiliary cancers often endure severe abdominal pain, which impacts their quality of life. This pain is usually a combination of both nociceptive and neuropathic pain, ...

Dane C McMillan, Yen-Chung Jonathan Wang, Kale B McMillan, Jayanth Adusumalli, David Powers ...

Ankylosing spondylosis (AS) is characterised by bilateral sacroiliitis, asymmetric peripheral oligoarthritis, association with the human leucocyte antigen-B27, enthesitis and dactylitis. The ...

Pulmonary artery stenosis (PAS) is most encountered in the paediatric population as a congenital anomaly. In adults, PAS from extrinsic compression of the pulmonary artery (PA) results from conditions ...

Investigations The size of the polyp was approximately 40 mm with moderate genital bleeding; however, the source of haemorrhaging was not clear. There was no subchorionic haematoma. The vascularised ...

Gastrointestinal stromal tumours (GISTs) are malignant mesenchymal tumours that originate from the interstitial pacemaker cells of Cajal. They are particularly rare, comprising only 5% of all GISTs, ...

Footnotes Contributors The following authors were responsible for drafting the text, sourcing and editing clinical images, investigating results, drawing original diagrams and algorithms and critical ...

Pink disease was once a widespread phenomenon, known to physicians throughout the Western world. Its prevalence declined massively once the source, mercury, was identified in several products. In ...

Description A woman in her 20s presented with an erythematous, itchy, scaly rash on her trunk and extremities for 3 weeks duration. She was otherwise healthy and had no history of taking any ...

A large percentage of the US population is either receiving or should be considered for statin therapy. Whether through primary or secondary prevention for atherosclerotic disease, statins remain one ...

Tracheobronchial inflammation and stenosis is an under-recognised and potentially life-threatening complication of granulomatosis with polyangiitis (GPA). Rituximab (RTX), in combination with ...