Aging-related cognitive decline is an early symptom of Alzheimer's disease and other dementias, and on its own can have substantial consequences on an individual's ability to perform important ...

MicroRNAs are short non-coding RNA molecules that regulate gene expression at the post-transcriptional level by guiding effector complexes to complementary sequences in target transcripts. In insects ...

PHILADELPHIA -- Researchers long thought that only one strand of a double-stranded microRNA can silence genes. Though recent evidence has challenged that dogma, it's unclear what the other strand does ...

Gene expression is controlled by numerous small RNA molecules called microRNAs, or miRNAs. However, specific functions of most miRNAs remain poorly understood. Working with worms, Friedrich Miescher ...

The 2024 Nobel Prize in Physiology or Medicine was awarded to Victor Ambros and Gary Ruvkun for their groundbreaking discovery of microRNA and its pivotal role in post-transcriptional gene regulation.

MicroRNAs are essential for Purkinje cells to develop their characteristically elaborate dendritic arbors. When Scripps Research scientists temporarily turned off microRNA function during development, ...

Comparative effectiveness of treatment strategies for urothelial cancer of the bladder (UCB) with clinical lymph node involvement (cN+). Anti-tumor activity, safety and pharmacokinetics (PK) of AGS15E ...

MicroRNAs are short RNA sequences that maintain a tight control on which genes are expressed and when. They do this by regulating which messenger RNA (mRNA) transcripts—the single-stranded templates ...

Please provide your email address to receive an email when new articles are posted on . The Nobel Assembly at Karolinska Institutet in Sweden announced the honor today. Victor R. Ambros, PhD, and Gary ...

Add Yahoo as a preferred source to see more of our stories on Google. It was well understood that proteins could mediate changes in gene expression as cells differentiate, divide. We were not looking ...

Could a common vitamin help treat fatty liver disease? See how new research links niacin to a hidden control switch in liver cells.