BACKGROUND AND OBJECTIVES: Evidence has revealed an important role in the use of medical cannabis, and the interaction of the endocannabinoid system with other drugs for the treatment of chronic ...

The 2023 focused update of the European Society of Cardiology 2021 guidelines reviewed the latest scientific evidence and provided recommendations for the guideline‐directed medical therapy for the ...

Novo Nordisk shares plunged after CagriSema failed to show non-inferiority to tirzepatide in the pivotal REDEFINE 4 Phase III obesity trial. CagriSema’s efficacy lagged, raising uncertainty about Novo ...

Although switching is usually safe and well tolerated, physician judgment concerning individual patient requirements must be maintained. The dose of the first- or second-generation β blocker that the ...

The aim of this study was to establish a pharmacodynamic model of tapentadol analgesia under dose titration conditions, to quantitatively analyze the time-effect relationship of the drug, and to ...

Lithium metal batteries (LMBs) hold tremendous potential for next-generation energy storage due to their high energy density, but their commercial adoption is hindered by poor stability and safety ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Foundation (L0) programs as an entry to degree courses are offered in many UK ...

‘I use the analogy of the difference between the books from the two original Bake Off hosts,’ to explain how the first year practical classes at the University of Strathclyde differ from traditional ...

Management of drug resistant epilepsy (DRE) represents a challenge to the treating clinician. This manuscript addresses DRE and provides an overview of treatment options, medical, surgical, and ...

Chronic liver disease (CLD) is a highly prevalent condition. There is burgeoning recognition that there are many people with subclinical liver disease that may nonetheless be clinically significant.