Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Tirzepatide (TZP), a 39-amino-acid synthetic peptide, is a once ...

Inactivating mutations in matrix Gla protein (MGP) lead to Keutel syndrome, a rare disease hallmarked by ectopic calcification of cartilage and vascular tissues. Although MGP acts as a strong ...