Beneath every garden bed, farm field, and forest floor, a single teaspoon of soil teems with billions of microorganisms, a population that dwarfs the roughly eight billion humans alive on the planet.

Department of Environmental Science and Engineering and International Environmental Research Center, Gwangju Institute of Science and Technology, Gwangju 500-712, Republic of Korea, Department of Soil ...

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cMolecular Medicine Research Group, Microbiology & Infectious Diseases, School of Medicine, Western Sydney University, Sydney, Australia dSurgical Infection Research Group, Faculty of Medicine and ...

Sequence variants are amino-acid substitutions that can influence biopharmaceutical efficacy and immunogenicity (1). Sequence variants could be considered as product-related impurities — molecular ...

Next-generation sequencing (NGS) is present in all fields of life science, which has greatly promoted the development of basic research while being gradually applied in clinical diagnosis. However, ...

There is growing interest in the role of DNA methylation in regulating the transcription of mitochondrial genes, particularly in brain disorders characterized by mitochondrial dysfunction. Here, we ...

Nucleic acid sequencing has become an integral part of modern biomedical research. The advances in sequencing technology, from its invention to modern-day equivalents, have been extraordinary. 2022 ...

The order of nucleotides within a sequence of DNA is important. It underpins subsequent protein function and, in cases of mutations, the subsequent disease manifestation. Determining the order of ...

Rapid advances in DNA sequencing technology (“next-generation sequencing”) have inspired optimism about the potential of human genomics for “precision medicine.” Meanwhile, pathogen genomics is ...

Epigenetic marks are chemical modifications found throughout the genome – the DNA within cells. By influencing the activity of nearby genes, the marks govern developmental processes and help cells to ...