bDepartment of Basic and Clinical Oncology and Center for Cancer Prevention and Control (CECAN), Faculty of Medicine, Universidad de Chile, Santiago, Chile ...

Breast and ovarian cancers are among the leading causes of cancer deaths around the world. Genetic association of families with a high risk of breast cancer has identified two major susceptibility ...

Approximately 75% of objective responses to anti–programmed death 1 (PD-1) therapy in patients with melanoma are durable, lasting for years, but delayed relapses have been noted long after initial ...

Recent large-scale WES studies have revealed the existence and relatively high frequency of somatic changes in HLA class I genes in head and neck cancer, squamous cell lung cancer, stomach ...

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Filaggrin is encoded by FLG, a highly unusual gene found within a cluster of more than 60 genes involved in epithelial differentiation (the epidermal differentiation complex, EDC). Uniquely, most of ...

Students model how scientists use DNA microarrays to determine levels of gene expression in breast cancer patients, and then choose treatments based on what they learn. Normal-functioning DNA codes ...

Segregation of INS mutations in 16 families. Squares represent male family members, and circles represent female members. Black circles and squares represent persons with diabetes. A slash mark ...