Raman spectroscopy enables real-time bioreactor monitoring of glucose and lactate without breaching the sterile boundary.

Retrofitting legacy bioprocessing equipment with modern PAT tools requires targeted sensor, software, and change-control ...

The seven companies listed here cover the realistic range of what a buyer will encounter in 2026: embedded ML teams that own ...

Abstract: A comprehensive literature survey of multivariate statistical process monitoring methods of recent years is presented. Principle component analysis based methods are reviewed according to ...

The biopharmaceutical industry is undergoing significant digital transformation. While this shift brings exciting opportunities, it also introduces increasing complexity and growing expectations for ...

Abstract: Detecting condenser abnormalities is essential to ensure the safe and efficient operation of thermal power plants. However, most of the existing methods do not consider relationships among ...

Biologics manufacturing entails multiple complex unit operations across three key process areas: cell culture, purification, and sterile fill–finish (Figure 1). Numerous raw materials are used to ...

Synchronization of variable trajectories from batch process data is a delicate operation that can induce artifacts in the definition of multivariate statistical process control (MSPC) models for ...