Inflammation promotes regeneration of injured tissues through poorly understood mechanisms, some of which involve interleukin (IL)-6 family members, the expression of which is elevated in many ...

Each substrate forms a 10-base-pair (bp) duplex with nucleotides 2–11 of the 12-nucleotide guide counted from box D/D′. The guide–substrate duplexes are placed in an RNA-binding channel formed by the ...