1 Alzheimer Centre and VU University Medical Centre, Amsterdam, The Netherlands 2 Department of Neurology, VU University Medical Centre, Amsterdam, The Netherlands 3 Department of Neurology and MRI ...

Positron emission tomography (PET) and magnetic resonance imaging (MRI) offer complementary information about the human brain in health and disease. The simultaneous 7 T MR-BrainPET insert enables ...

Cerebrospinal fluid-interstitial fluid (CSF–ISF) exchange is central to brain clearance, yet quantitative measurements in humans have been lacking. We establish an MRI approach that enables ...

aDepartment of Pediatric Cardiology, Division of Pediatrics, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, Netherlands bDepartment of Neonatology, Division of Woman and ...

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Chiari malformation, an anomaly of the posterior cranial fossa, also known as Arnold–Chiari malformation, was described in autopsies by Hans Chiari, an Austrian pathologist, in 1891. He defined four ...

Background There is a need for biomarkers of disease progression and therapeutic response in multiple sclerosis (MS). This study aimed to identify cerebrospinal fluid (CSF) lipids that differentiate ...

In this first-in-human, investigator-initiated, open-label study, three participants with recurrent glioblastoma were treated with CARv3-TEAM-E T cells, which are chimeric antigen receptor (CAR) T ...

The glymphatic pathway was defined in rodents as a network of perivascular spaces (PVSs) that facilitates organized distribution of cerebrospinal fluid (CSF) into the brain parenchyma. To date, ...

Four-dimensional flow magnetic resonance imaging (MRI) has evolved as a non-invasive imaging technique to visualize and quantify blood flow in the heart and vessels. Hemodynamic parameters derived ...

This study aimed to evaluate the prognostic value of hyperemic coronary sinus flow (h‐CSF) and global coronary flow reserve (g‐CFR) obtained by phase‐contrast cine‐magnetic resonance imaging in ...