Imaging technique has emerged as an innovative tool for diagnosing and monitoring patients with pulmonary hypertension (PH). Current studies in radiomics primarily focus on hemodynamics and cardiac ...

To prevent disease, it is of great importance to detect the critical point (pre-disease state) when the biological system abruptly transforms from normal to disease state. However, rapid and accurate ...

aInstitute of Precision Medicine, Peking University Shenzhen Hospital, Shenzhen 518036, China bInstitute of Systems Biomedicine, Department of Pathology, School of Basic Medical Sciences, ...

1Centre for Evolution and Cancer, The Institute of Cancer Research, London, United Kingdom. 2Division of Molecular Pathology, The Institute of Cancer Research, London, United Kingdom. Search for other ...

cDepartment of Respiratory Medicine, Charing Cross Hospital, Imperial College Healthcare Trust, Fulham Palace Road, London, W6 8RF, UK dDepartment of Respiratory Medicine, University College London ...

KTH Royal Institute of Technology, Department of Chemistry, Division of Surface and Corrosion Science, 100 44 Stockholm, Sweden KTH Royal Institute of Technology, Department of Chemistry, Division of ...

Fig. 2: Clonal haematopoiesis is a major source of cfDNA variants and molecular features distinguish clonal haematopoiesis-derived from tumour-derived cfDNA variants. In individuals that do not have a ...

Early detection of pancreatic cancer is challenging because cancer-specific symptoms occur only at an advanced stage, and a reliable screening tool to identify high-risk patients is lacking. To ...

In designing new nanoparticle drug delivery systems, it is critical to identify simple formulations that overcome multiple biological barriers while being safe, reproducible, and scalable. We modified ...

Cancers appear as disordered mixtures of different cells, which is partly why they are hard to treat. We show here that despite this chaos, tumors show local organization that emerges from cellular ...

Primary lung cancer remains the leading cause of cancer-related death in the Western world, and the lung is a common site for recurrence of extrathoracic malignancies. Small-animal (rodent) models of ...