Genome editing lets scientists rewrite DNA, the instruction manual inside every living cell, with a precision that was unthinkable a generation ago. Technologies such as CRISPR have made this almost ...

Bioinformatics is the foundation of modern research, translating complex biological data into actionable insights by combining biology, computer science, and data analysis. Selecting the right ...

We are living in an era where biology has become synonymous with big data due to the ever-increasing amount of data being generated by technologies such as next-generation sequencing. Bioinformatics ...

The reliability of multiple sequence alignment (MSA) results directly determines the credibility of the conclusions drawn from biological research. However, MSA is inherently an NP-hard problem, ...

Abstract: In this paper we present a homomorphic computation algorithm that finds an optimal local alignment of a pair of encrypted sequences, based on the Smith-Waterman recurrence. Our algorithm ...

The LocARNA package provides several tools for the structural analysis of RNA. LocARNA's main functionality is to align a set of a priori unaligned RNAs sequences and at the same time predict their ...

ABSTRACT: Systems biology, an emerging field, investigates the interactions of genes and drug actions across various levels of complexity, ranging from molecular and cellular to tissue and organism ...

This important study addresses the problem of detecting weak similarity between protein sequences, a procedure commonly used to infer homology or assign putative functions to uncharacterized proteins.