In the food-borne pathogen Listeria monocytogenes, virulence genes are expressed at 37°C, but not 30°C. This process is under the control of PrfA — a transcriptional activator thermoregulated by a ...

李斯特菌prfA转录因子靶向抑制研究：通过计算对接和分子动力学模拟评估蜂胶化合物的抑制活性，发现其与prfA结合稳定且自由能低，为抑制李斯特菌致病性提供新策略。 摘要 单核细胞增生李斯特菌是全球恶性李斯特菌病的致病菌，由于耐药性的出现和死亡率的 ...

第1眼TV-华龙网讯（记者 刘艳）“五一”来重庆，又有新体验。重庆交通开投公交集团西部分公司开行观光巴士D280线，带游客一站式打卡“甲亢哥”来渝旅行同款线路，沉浸式体验立体山城的魅力。 西部公交供图 据介绍，D280线以解放碑为起点，全程约22公里 ...

编辑推荐：本研究针对李斯特菌毒力调控关键因子PrfA的抑制机制不明问题，通过结构生物学手段解析了环境寡肽以序列非依赖方式竞争性占据GSH结合位点的分子机制，发现β折叠样相互作用介导的混杂性结合模式及疏水残基选择性识别特征，为病原菌环境适应与 ...

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JavaScript frameworks play a crucial role in today’s web application developments as they help developers build effective, flexible, and best web applications. These frameworks make otherwise ...

Abstract: This paper aims to use an experimental approach to determine the best performing and most stable web programming languages for building a website. Through a comprehensive comparison of ...

Learn about the best practices for web development and JavaScript programming, complete with code examples and real-world scenarios. JavaScript is a versatile and widely used programming language that ...

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This study compared the effectiveness and safety of laparoscopic radiofrequency ablation (LRFA) and percutaneous radiofrequency ablation (PRFA) in the treatment of hepatitis B virus (HBV)-related ...