The complement system, a coordinator and facilitator of the innate immune response, plays an essential role in maintaining host homeostasis. It promotes clearance of pathogen- and danger-associated ...

This fundamental study significantly advances our understanding of how parasites evade the host complement immune system. The new cryo-EM structure of the trypanosome receptor ISG65 bound to ...

Covid-19 denotes coronavirus disease 2019, CT computed tomography, ICU intensive care unit, MIS-C multisystem inflammatory syndrome in children, ND not determined, PASC postacute sequelae of Covid-19, ...

Chronic inflammatory demyelinating polyneuropathy (CIDP) is the most common, heterogeneous, immune-mediated neuropathy, characterized by predominant demyelination of motor and sensory nerves. CIDP ...

Humoral immunity produces antigen-specific antibodies and is primarily driven by B cells. Cell-mediated immunity on the other hand does not depend on antibodies for its adaptive immune functions and ...

One can acquire humoral immunity to a specific infection or disease if administered with antibodies from someone who was previously been exposed to the same infection, circumventing the humoral ...

Insights into the important contribution of inflammation and immune functions in the development and progression of atherosclerosis have greatly improved our understanding of this disease. Although ...

IgM antibodies protect mammals against humoral microbial infection and mediate clearance of cellular debris. IgM activates the immune complement system only after binding to cell-surface antigens.

The complement system is a major pillar of the humoral innate immune system. As a first line of defense against pathogens, it mediates early inflammatory response and links different branches of ...

The mammalian immune system is a remarkable complex of biochemical processes enabling efficient detection and prosecution of pathogens that threaten host viability. The incredible complexity of ...

The lesions of Stx-related hemolytic–uremic syndrome, which are indistinguishable from those of its atypical form on the basis of standard histologic analysis, are characterized by thickening of ...