Department of Chemistry, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, 130 Scripps Way, Jupiter, Florida 33458, United States Department of Chemistry, The Scripps ...

DNA sequencing-based studies of neurodevelopmental disorders (NDDs) have identified a wide range of genetic determinants. However, a comprehensive analysis of these data, in aggregate, has not to date ...

PolyQ diseases include dentatorubral-pallidoluysian atrophy (DRPLA), Huntington’s disease (HD), spinal and bulbar muscular atrophy (SBMA, also known as Kennedy’s ...

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The diamide insecticide class is one of the top-selling insecticides globally. They are used to control a wide range of pests by targeting their ryanodine receptors (RyRs). Here, we report the highest ...

Engagement is a concept of the utmost importance in human-computer interaction, not only for informing the design and implementation of interfaces, but also for enabling more sophisticated interfaces ...

Starch is the main carbohydrate storage molecule in plants and is ubiquitous in human life. Reversible starch phosphorylation is the key regulatory event in starch catabolism. Starch Excess4 (SEX4) ...

Human plasma low-density lipoproteins (LDL), a risk factor for cardiovascular disease, transfer cholesterol from plasma to liver cells via the LDL receptor (LDLr). Here, we report the structures of ...