Objective High-flow nasal cannula (HFNC) therapy is increasingly used in preterm infants despite a paucity of physiological studies. We aimed to investigate the effects of HFNC on respiratory ...

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The notion that acute respiratory distress syndrome (ARDS) is a heterogeneous syndrome is a ubiquitous finding as old as the concept of ARDS itself, contributing substantially to the complexity of its ...

Introduction High-flow nasal oxygen (HFNO) use in adults hospitalised with acute respiratory failure (ARF) is increasing. However, evidence to support widespread use of HFNO compared with non-invasive ...

The innate immune response plays an important role in the pathophysiology of acute respiratory distress syndrome (ARDS); however, no drug has been proven to be beneficial in the management of ARDS.

Acute respiratory distress syndrome (ARDS) is a devastating clinical syndrome that leads to acute respiratory failure and accounts for over 70,000 deaths per year in the United States alone, even ...

cDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine, Departments of Medicine and Anesthesia, University of California San Francisco, San Francisco, CA, USA Acute respiratory distress ...

Objectives COVID-19 causes lung parenchymal and endothelial damage that lead to hypoxic acute respiratory failure (hARF). The influence of hARF severity on patients’ outcomes is still poorly ...

1 Department of Thoracic Medicine, Wexham Park Hospital, Frimley Health Foundation Trust, Slough, SL2 4HL, UK 2 Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford University Hospitals ...