bDepartment of Medicine III, University Hospital Rheinisch-Westfälische Technische Hochschule Aachen, Aachen, Germany cDepartment of Diagnostic and Interventional Radiology, University Hospital ...

Heart failure with preserved ejection fraction (HFpEF) is a poorly understood, multisystem disease with high morbidity and mortality. To improve understanding of its pathobiology, we analyzed ...

Captured while iterating on the scmultiomics branch (single-cell multi-omics report layered on top of an annotated ScSeurat output). For deployment and submission ...

Myocardial infarction (MI) is a leading cause of death worldwide and can eliminate up to a third of the cardiomyocytes within the human heart. Although cardiomyocytes undergo mitosis during early ...

Unsaturated fatty acids are critical for maintaining membrane fluidity, cellular signaling, and lipid storage. Stearoyl-CoA desaturase (SCD) regulates the dynamics between saturated and unsaturated ...

To overcome the above-mentioned challenges, here we rebuilt ABioTrans as a new webserver and expanded its functionality to include several new analysis tools such as SOM, t-SNE, random forest ...

Gene regulatory networks underpin stress response pathways in plants. However, parsing these networks to prioritize key genes underlying a particular trait is challenging. Here, we have built the Gene ...

The concordance of RNA-sequencing (RNA-seq) with microarrays for genome-wide analysis of differential gene expression has not been rigorously assessed using a range of chemical treatment conditions.

Whether organisms can inherit environmental adaptations acquired by their parents remains a longstanding question in biology. In plants, seed behavior such as dormancy, germination, and ...

It is expected that emerging digital gene expression (DGE) technologies will overtake microarray technologies in the near future for many functional genomics applications. One of the fundamental data ...