Homolog detection, finding similar proteins to an unknown protein, is usually the first step in understanding the role and function of that protein. However, if the identity of protein sequences ...

Edit distance—a classical problem in computer science—has received ongoing attention from both practitioners and theoreticians. Given two strings A and B, the edit distance is the minimum number of ...

In recent years, there has been an explosive increase in the amount of bioinformatics data produced, but data are not information. The purpose of bioinformatics research is to obtain information with ...

To evaluate the result generated by the ZSDP approach against standard sequence alignments, we compared the genome annotation files with RNA-seq results using Cufflinks v2.2.1 (Trapnell et al., 2012).

Polyketides (PKs) and nonribosomal peptides (NRPs) are profoundly important natural products, forming the foundations of many therapeutic regimes. Decades of research have revealed over 11,000 PK and ...

As the United States takes another step this week toward determining who will be on the ballot in November, the nation's brightest emerging leaders will be meeting at the Woodrow Wilson Center to ...