Motivation to work for potential rewards is critically dependent on dopamine (DA) in the nucleus accumbens (NAc). DA release from NAc axons can be controlled by at least two distinct mechanisms: (1) ...

Across sensory systems, complex spatio-temporal patterns of neural activity arise following the onset (ON) and offset (OFF) of stimuli. While ON responses have been widely studied, the mechanisms ...

Spastic paresis (SP) is the most commonly diagnosed impairment in children with cerebral palsy or hereditary spastic paraplegia, and the most common cause for physical disability in children (Cans et ...

Signaling pathways must decide how to respond to extracellular stimulation patterns that vary widely in vivo. However, most experiments only explore how cells respond to one stimulation variable: ...

PSYCHOACOUSTICS is a new MATLAB toolbox which implements three classic adaptive procedures for auditory threshold estimation. The first includes those of the Staircase family (method of limits, simple ...

The brain performs computations by transforming sensory inputs to make decisions. We study these neuronal computations in the mouse, one of the smallest animals with a cerebral cortex, the part of the ...