Background: In this paper, the basic elements related to the selection of participants for a health research are discussed. Sample representativeness, sample frame, types of sampling, as well as the ...

High-entropy alloys (HEAs) open up new doors for their novel design principles and excellent properties. In order to explore the huge compositional and microstructural spaces more effectively, ...

Adam Hayes, Ph.D., CFA, is a financial writer with 15+ years Wall Street experience as a derivatives trader. Besides his extensive derivative trading expertise, Adam is an expert in economics and ...

Effect sizes are the most important outcome of empirical studies. Most articles on effect sizes highlight their importance to communicate the practical significance of results. For scientists ...

Ethics committees require estimates of sample size for all trials, but statistical calculations are no more accurate than estimates from historical data. Geoffrey Norman and colleagues propose some ...

Matched case-control design is a type of stratification for the control of confounding at the design stage. One of basic premises is a 1:M matched case-control study, where each case is matched with ...

Martin Bland’s extensive experience in reviewing and using power calculations has led him to believe that it is time to replace them When I began my career in medical statistics, back in 1972, little ...

Epistatic interactions among multiple genetic variants in the human genome may be important in determining individual susceptibility to common diseases. Although some existing computational methods ...

Is your chip fast enough? Is it too fast? Systems engineers might be paying for more chip than they need, or they may be dangerously close to over-taxing their current processor. Take the guesswork ...