pggb builds pangenome variation graphs from a set of input sequences. A pangenome variation graph is a kind of generic multiple sequence alignment. It lets us understand any kind of sequence variation ...

Genomic medicine relies on single reference genomes that miss crucial genetic diversity, creating diagnostic gaps that disproportionately affect underrepresented populations. Pangenome graphs, ...

Many biological networks are modeled with multivariate discrete dynamical systems. Current theory suggests that the network of interactions captures salient features of system dynamics, but it misses ...

The dual-channel graph convolutional neural networks based on hybrid features jointly model the different features of networks, so that the features can learn each other and improve the performance of ...

Global, regional, and country/territory-level data on key dimensions of human development, with interactive insights and publications. The human development data are globally comparable, linked to the ...

In this article, we explore how Postgres, a powerful and versatile relational database, can be effectively used to model and traverse graphs and trees. While specialized graph databases exist, such as ...

Department of Computer Science and Engineering, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, South Korea Autonomous Materials Development LAB, Samsung Advanced Institute of ...

Error correction is the canonical first step in long-read sequencing data analysis. Current self-correction methods, however, are affected by consensus sequence ...

Introduction Use of home dialysis by centres in the UK varies considerably and is decreasing despite attempts to encourage greater use. Knowing what drives this unwarranted variation requires in-depth ...

There are three key aspects to genetic disease associations: comprehensive variant discovery, accurate allele-frequency determination, and an understanding of the pattern of normal variation and its ...

For small genomes, it is possible to study genetic variation by assembling whole genomes and then comparing them via whole-genome comparison 6,7. For large genomes, such as the human genome, complete ...