Figure 1: RNA-seq data uses short reads of mRNA which is free of intronic non-coding DNA. These reads must then be aligned back to the reference genome. Credit: Technology Networks. Early RNA-seq ...

Background: The epidemiologic transition in Mexico has generated a change of paradigm in public health. Morbidity is characterized by infectious diseases and the mortality is due to chronic ...

We performed a systematic analysis of blood DNA methylation profiles from 4483 participants from seven independent cohorts identifying differentially methylated positions (DMPs) associated with ...

The intellectual property, genetic resource prior informed consent, and access & benefit sharing landscape is currently in flux. The new laws and agreements being developed at the national and ...

Cellular repair enzymes remove virtually all DNA damage before it is fixed; repair therefore plays a crucial role in preventing cancer. Repair studied at the level of transcription correlates poorly ...

The combination of molecular self-assembly based on the DNA origami technique with lithographic patterning enables the creation of hierarchically ordered nanosystems, in which single molecules are ...

DNA methylation, especially CpG methylation at promoter regions, has been generally considered as a potent epigenetic modification that prohibits transcription factor (TF) recruitment, resulting in ...

Different applications have different requirements, so researchers need to carefully weigh their options when deciding whether to switch to a new platform. [© WavebreakmediaMicro – Fotolia.com] With ...

Chromosomal microarray analysis has emerged as a primary diagnostic tool for the evaluation of developmental delay and structural malformations in children. We aimed to evaluate the accuracy, efficacy ...

bDepartment of Clinical Microbiology, University College London Hospitals NHS Foundation Trust and Centre for Infectious Diseases and International Health, University College London Medical School, ...

Array painting is a technique that uses microarray technology to rapidly map chromosome translocation breakpoints. Previous methods to map translocation breakpoints have used fluorescence in situ ...

Optical addressing of semiconductor electrodes represents a powerful technology that enables the independent and parallel control of a very large number of electrical phenomena at the ...