For decades, the accepted explanation for the origins of the Japanese people was relatively straightforward. Modern Japanese populations were understood to descend from two major ancestral groups: the ...

For years, scientists believed the origins of the Japanese population could be traced back mainly to two ancient groups. But a major new DNA study is now challenging that long-held belief and ...

Scientists analyzing the genomes of thousands of people across Japan discovered evidence for a previously overlooked third ancestral group, challenging the long-accepted “dual origins” theory. The ...

Imagine you're a detective, but instead of solving crimes, you're uncovering the secrets hidden within our genes. Every cell in your body is constantly "talking" through gene expression, and ...

Figure 1: RNA-seq data uses short reads of mRNA which is free of intronic non-coding DNA. These reads must then be aligned back to the reference genome. Credit: Technology Networks. Early RNA-seq ...

Identify the cause of a person's epilepsy. Diagnosis accurately and provide the best possible medical management. Help individuals with genetic epilepsy disorders whose seizures are not ...

State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences-Beijing (PHOENIX Center), Beijing Institute of Lifeomics, Beijing 102206, China ...

Microarrays are a two-dimensional arrangement of biological samples, with samples placed in spots numbering in the thousands and organized into columns and rows. They allow for efficient analysis of ...

Two weeks ago, Sen. Elizabeth Warren released the results of a genetic test showing she has a small but detectable amount of Native American DNA. The report concluded there is “strong evidence” she ...

Testing for trisomy 21 is shown as an illustrative example. In random sequencing, cell-free DNA (cfDNA) fragments originating from any chromosome are sequenced. A random representative selection of ...

SLE is a complex autoimmune disease that results from the interplay of genetics, epigenetics and environmental exposures. DNA methylation is an epigenetic mechanism that regulates gene expression and ...

Cellular repair enzymes remove virtually all DNA damage before it is fixed; repair therefore plays a crucial role in preventing cancer. Repair studied at the level of transcription correlates poorly ...