Novel immune reprogramming oral macrocyclic peptides designed for precise modulation of complex biological networks involved in inflammatory, autoimmune and fibro-inflammatory diseases ...

Effects of resorcinol isoprenyl benzene derivative IPI201 on natural killer cell cytotoxicity and tumor cell viability in human colorectal adenocarcinoma cells. An LNP-mRNA–based in vivo cell engager ...

To continue reading this content, please enable JavaScript in your browser settings and refresh this page. Preview this article 1 min Executives behind three ...

Unlock the full InfoQ experience by logging in! Stay updated with your favorite authors and topics, engage with content, and download exclusive resources. Martin Kleppmann, an associate professor at ...

Summary: Researchers have demonstrated that memory decline and symptoms of Alzheimer’s may not be irreversible. By using “partial reprogramming” on specific groups of neurons called engrams—the cells ...

Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory pulmonary disease marked by persistent airflow obstruction. Its heterogeneity is manifested in parenchymal destruction and airway ...

Who said free-to-air TV was in its death throes? When the Seven news network ran a piece about Paradigm Biopharmaceuticals’ (ASX:PAR) knee osteoarthritis (OA) drug candidate a few months ago, the ...

The accumulation of lactate in synovial microenvironment of rheumatoid arthritis (RA) patients is closely correlated with disease activity, with elevated lactate levels serving as both biomarkers and ...

The next leap in Industrial AI isn‘t just algorithms. It‘s machines that reason, act and adapt! Welcome to this edition of the Spotlight AI! In this month's newsletter, we will take a closer look at ...

The era of AI-powered programming is upon us, and it’s not just a supporting act; it’s stealing the limelight. AI is already rewriting the rules of code creation. However, this is just the tip of the ...

Mechanisms specifying cancer cell states and response to therapy are incompletely understood. Here we show epigenetic reprogramming shapes the cellular landscape of schwannomas, the most common tumors ...