宝子们！做药物研发或疾病机制研究时，你是不是也遇到过这种困惑：想找疾病相关的候选基因，翻遍文献却效率低下？想查某个药物的作用靶点，面对五花八门的数据库不知道从何下手？ 其实，疾病靶点预测的核心，在于用好各类生物信息数据库—— 它们就 ...

ODDPub is a text mining algorithm that parses a set of publications and detects which publications disseminated Open Data or Open Code together with the publication. It is tailored towards biomedical ...

Background Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal cancer with a 5-year survival rate of 12%. It has two major molecular subtypes: classical and basal, regulated by the master ...

The COVID-19 pandemic had a profound effect on the world, resulting in a dramatic loss of human lives. While the situation is now largely under control, there are patients who still suffer from the ...

The COVID-19 pandemic had a profound effect on the world, resulting in a dramatic loss of human lives. While the situation is now largely under control, there are patients who still suffer from the ...

The physiology and behavior of living organisms are featured by time-related variations driven by molecular clockworks that arose during evolution stochastically and heterogeneously. Over the years, ...

传统化疗是对抗癌症的常见方法，但它会攻击全身，造成不必要的副作用，如脱发，恶心和疲劳。 靶向治疗选择性地杀死癌细胞而不影响健康组织。靶向药物开发将成为治疗癌症的重要手段。 肿瘤的生物信息学数据库对肿瘤基础研究的发展、临床治疗水平提供 ...

Vascular smooth muscle cells (VSMCs) show a remarkable phenotypic plasticity, allowing acquisition of contractile or synthetic states, but critical information is missing about the physiologic signals ...

ASCO’s manuscript guidelines regarding human investigation will apply to the treatment of data derived from human investigations. In particular, authors should take care to anonymize their data to ...