Pharmacokinetic parameter calculations (Cmax, AUC, Tmax, t½) Concentration-time profile analysis Dose-exposure-response relationships Understanding of NONMEM input data requirements ...

To provide an open source, modularized toolbox that enables the pharmaceutical programming community to develop ADaM datasets in R. Provide users with an open source, modularized toolbox with which to ...

Continuous medical and safety monitoring of subject data during a clinical trial is a critical part of evaluating the safety of trial participants and as such is governed by protocol procedures and ...

The conect4children (c4c) project aims to facilitate efficient planning and delivery of paediatric clinical trials. One objective of c4c is data standardization and reuse. Interoperability and ...

The Clinical Data Interchange Standards Consortium, or CDISC, creates medical research standards for the healthcare and pharmaceutical industry, especially for medical research such as clinical trials ...

The Clinical Data Interchange Standards Consortium (CDISC) is dedicated to the improvement of medical research through data standardization. CDISC has produced a suite of standards that should be used ...