Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, United States Neuroscience Interdepartmental Program, University of California, Los ...
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In the last decades, important progress has been achieved in the understanding of the neurotrophic effects of intermittent fasting (IF), calorie restriction (CR) and exercise. Improved neuroprotection ...
Cryogenic electron microscopy (cryo-EM) single-particle methods strive to create accurate, high-resolution three-dimensional maps of macromolecules. Depending on many factors, including imaging ...
Interdisciplinary Biomedical Research Centre, School of Science and Technology, Nottingham Trent University, Clifton Lane, Nottingham NG11 8NS, United Kingdom Interface and Surface Analysis Centre, ...
An increasing number of protein structures have been determined by cryo-electron microscopy taking advantage of recent technological advancements which have enabled structure determinations at ...
The potential effect of conformational dynamics of enzymes on their chemical steps has been intensely debated recently. We use single-molecule FRET experiments on adenylate kinase (AK) to shed new ...