This cover highlights the article Mechanical strain stimulates COPII-dependent secretory trafficking via Rac1 by Santosh Phuyal, Pere Roca-Cusachs, Hesso Farhan and colleagues. This study reports on a ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Piccolino regulates ribbon morphology as well ...

The inactivation of glycogen synthase kinase (GSK)3 has been proposed to play important roles in insulin and Wnt signalling. To define the role that inactivation of GSK3 plays, we generated homozygous ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Kareniacean plastids are distinct from those ...

Rab GTPases have emerged as critical regulators of intracellular transport and have been proposed to define functional domains within the endomembrane system (Zerial and McBride, 2001). Rab function ...

Cortical neurogenesis depends on the balance between self‐renewal and differentiation of apical progenitors (APs). Here, we study the epigenetic control of AP's division mode by focusing on the ...

Owing to advances in genome sequencing, genome stability has become one of the most scrutinized cellular traits across the Tree of Life. Despite its centrality to all things biological, the mutation ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Signaling via small extracellular vesicles ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Astrocytes in the brain exhibit regional ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Transposable elements (TEs) are mobile genetic ...

The question of how the same extracellular stimulus can in different contexts lead to a multiplicity of cell fates is central to all developing biological systems. In T‐cell development, this is ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Reversible disassembly is a highly conserved ...