Atlastin, a member of the dynamin superfamily, is known to catalyse homotypic membrane fusion in the smooth endoplasmic reticulum (ER). Recent studies of atlastin have elucidated key features about ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. CD8 + T cells have critical roles in tumor ...

Naïve T helper (Th) cells differentiate in response to antigen stimulation into either Th1 or Th2 effector cells, which are characterized by the secretion of different set of cytokines. Th2 ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. This work employs adult polyglucosan body ...

Figure 3. NRIF is polyubiquitinated by the E3 ubiquitin ligase TRAF6. HEK 293 cells were cotransfected with Flag‐NRIF, Flag‐TRAF6 or HA‐ubiquitin, then lysed in SDS lysis buffer and the lysates were ...

Here, we used CaMV–TAV as a tool to fish for cellular proteins that could function in the activation of polycistronic mRNA translation. We report a new plant protein—‘Re‐Initiation Supporting Protein’ ...

The TREX complex is involved in both transcription elongation and mRNA export and is recruited to nascent transcription complexes. We have examined Yra1p, Sub2p and Hpr1p recruitment to nine genes of ...

Normal cell growth is governed by a complicated biological system, featuring multiple levels of control, often deregulated in cancers. The role of microRNAs (miRNAs) in the control of gene expression ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Auxin dictates root architecture via the Auxin ...

Department of Microbiology and Division of Developmental and Clinical Immunology, University of Alabama at Birmingham, Birmingham, AL, 35294-3300 USA ...

The human body strives to control the concentration of blood glucose within a narrow range, by using counterbalancing hormones. When we ingest sugar, the surge in blood glucose triggers the release of ...

The spatiotemporal regulation of cAMP can generate microdomains just beneath the plasma membrane where cAMP increases are larger and more dynamic than those seen globally. Real‐time measurements of ...