These findings highlight the dual roles of antioxidants in cancer. Their impact depends on cancer type, stage, and genetic ...

Here we identified the marine algal toxin Portimine A produced by the dinoflagellate V ulcanodinium rugosum as a driver of skin inflammation in humans. Specifically, PortimineA-inactivated translation ...

Facundo D. Batista (Chief Editor) Facundo is the Phillip T. and Susan M. Ragon Professor of Microbiology and Immunology at Harvard Medical School, and Associate Director of the Ragon Institute of MGH, ...

After being informed of a potential microduplication in Figure 1D, the journal contacted the authors for clarification. The ...

The EMBO Journal publishes papers describing original research of broad general interest in molecular and cell biology - a particular emphasis is placed on molecular mechanism and physiological ...

Plants produce a wide diversity of compounds. Broadly, these are separated into primary metabolites, which are necessary for ...

N6-methyladenosine (m 6 A) exerts many of its regulatory effects on eukaryotic mRNAs by recruiting cytoplasmic YT521-B homology-domain family (YTHDF) proteins. Here, we show that in Arabidopsis ...

Copine-6, also known as N-Copine (Neuronal-Copine), is a calcium-dependent phospholipid-binding protein of the Copine family (Copine 1–9, coded for by Cpne1-9 genes) (Creutz et al, 1998; Khvotchev and ...

Thymic stromal lymphopoietin (TSLP) is a key player in atopic diseases, which has sparked great interest in therapeutically targeting TSLP. Yet, no small-molecule TSLP inhibitors exist due to the ...

Skeletal muscle is a highly plastic tissue that is capable of making up for turnover caused by daily wear-and-tear as well as regenerating upon damage (Furrer and Handschin, 2019). Myogenesis is ...

The release of the neural network-based software AlphaFold (AF) was not only a breakthrough for the prediction of monomeric structures of proteins (Jumper et al, 2021) but multiple studies published ...

The exposure of PtdSer is controlled by the balance of its scrambling and internalization (Lemke, 2019). PtdSer is ubiquitously present on the intracellular leaflet of the plasma membrane of ...