Plants produce a wide diversity of compounds. Broadly, these are separated into primary metabolites, which are necessary for ...

EMBO Press publishes five scientific journals: The EMBO Journal - Submit here The EMBO Journal has been EMBO's flagship publication for 40 years. With a scope that spans all areas of molecular biology ...

Prostate cancer (PCa) is the second most frequently occurring cancer and the fifth leading cause of cancer mortality among men worldwide in 2022 (Bray et al, 2024). Androgen receptor (AR) is ...

Facundo D. Batista (Chief Editor) Facundo is the Phillip T. and Susan M. Ragon Professor of Microbiology and Immunology at Harvard Medical School, and Associate Director of the Ragon Institute of MGH, ...

N6-methyladenosine (m 6 A) exerts many of its regulatory effects on eukaryotic mRNAs by recruiting cytoplasmic YT521-B homology-domain family (YTHDF) proteins. Here, we show that in Arabidopsis ...

MCM8 deficiency impairs meiotic homologous recombination repair, but the specific role of MCM8 in mitotic germ cells remains poorly understood. This study reveals that MCM8 interacts with helicase ...

Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype, characterized by extensive intratumoral heterogeneity, high metastasis, and chemoresistance, leading to poor clinical ...

Atg13 plays a crucial role in autophagy by forming a complex with Atg1, the homolog of mammalian ULK1 and a key protein kinase involved in autophagy. This complex interacts with the dimeric ...

While cellular metabolism impacts the DNA damage response, a systematic understanding of the metabolic requirements that are crucial for DNA damage repair has yet to be achieved. Here, we investigate ...

Rheumatoid arthritis (RA) is associated with heart and lung dysfunction. Current therapies fail to attenuate such complications. Here, we identify formyl-peptide receptor type 2 (FPR2) as a ...

The signal recognition particle (SRP) is a ribonucleoprotein particle essential for the targeting of signal peptide‐bearing proteins to the prokaryotic plasma membrane or the eukaryotic endoplasmic ...

The human mammary gland represents a highly organized and dynamic tissue, uniquely characterized by postnatal developmental cycles. During pregnancy and lactation, it undergoes extensive ...