Steps Forward: Immunoassays for cryptic HDGFL2 flag TDP-43 proteinopathy in diverse disorders. Companies have moved a PET ligand into Phase 1 trials.

A documentary of country legend Glen Campbell's life and “Goodbye Tour” following his diagnosis of Alzheimer's ...

Anatomy explorers have charted a new path myeloid cells use to access the brain. On 3 June in Neuron, scientists led by Lindsay Hohsfield and Kim Green, both at the University of California, Irvine, ...

Massage might help your brain flow regain its mojo. On June 4 in Nature, researchers led by Gou Young Koh at the Institute for Basic Science in Daejeon, South Korea, mapped the labyrinth of lymphatics ...

To narrow down the number of scents needed for such a test, Li first ranked each of the 16 SST-ID and 40 UPSIT scents for their ability to distinguish PD/DLB from controls in three cohorts—the De Novo ...

Background Sensory Stimulation Systems, and GENUS, refer to a noninvasive procedure, i.e., a "digital therapeutic," being developed by Cognito Therapeutics. The company developed a wearable GammaSense ...

Since February, the termination of some 2,482 grants worth $8.6 billion has shaken the scientific community, including AD researchers. Thanks to government databases and intrepid scientists tracking ...

Leucine-rich repeat kinase 2 encodes a large, complex protein containing a kinase, a GTPase, and multiple protein-protein interaction domains. The interplay of its enzymatic kinase and signaling ...

Other Phenotypes Premature death, attributed to hindbrain tauopathy, generally occurs between eight and 12 months (Dutschmann et al., 2010). Premature death is preceded by weight loss, hyperkyphosis, ...

Award Awards will be for up to $475,000 in Direct Costs per year, plus applicable Facilities and Administrative (F&A) costs.

To test for links between viral immune response and dementia, the researchers focused on a subgroup of 91 people with dementia and 98 healthy controls who tested negative for amyloid. They found that ...

Award NIH intends to commit approximately $8 million in FY 2026 to fund approximately 8 awards. Awards will be for $700,000 in Direct Costs per year, plus applicable Facilities and Administrative ...