As a chronic progressive disease, Parkinson's disease (PD) has a presymptomatic interval; that is, a period during which the pathological process has begun, but motor signs required for the clinical ...

Faculty of Medicine MS/MRI Research Group, University of British Columbia, Vancouver, Canada Helen Tremlett, PhD, Department of Medicine (Neurology), rm S178, 2211 Wesbrook Mall, University of British ...

OBJECTIVES Neuropsychological investigations have shown a degree of cognitive dysfunction in a proportion of non-demented patients with ALS. Respiratory muscle weakness in ALS can lead to nocturnal ...

Correspondence to Dr Timothy Rittman, Department of Clinical Neurosciences, University of Cambridge, Herchel Smith Building, Forvie Site, Addenbrooke's Hospital Site, Robinson Way, Cambridge CB2 0SZ, ...

Objectives We aimed to compare the long-term outcomes and surgical benefits between moyamoya disease (MMD) and atherosclerosis-associated moyamoya vasculopathy (AS-MMV) using high-resolution MRI ...

NHS Department of Clinical Neurosciences, Western General Hospital, and School of Molecular and Clinical Medicine, University of Edinburgh, Edinburgh, UK Correspondence to: Dr Jon Stone Department of ...

Institute of Neuroscience, Department of Neurology, University of Helsinki, Finland Dr Laura Hokkanen, Institute of Neuroscience, Department of Neurology, University of Helsinki, Finland. OBJECTIVE ...

The brain is in a constant state of dynamic change, for example switching between cognitive and behavioural tasks, and between wakefulness and sleep. The brains of people with epilepsy have additional ...

Correspondence to Professor Yoon-Ho Hong, Neurology, Neuroscience Research Institute, Medical Research Council, Seoul National University College of Medicine, Seoul Metropolitan Government Boramae ...

Parkinson’s disease (PD) is an incurable and progressive neurological disorder leading to deleterious motor and non-motor consequences. Presently, no pharmacological agents can prevent PD evolution or ...

Background Calorie restriction (CR) ameliorates preclinical models of multiple sclerosis (MS) via multiple mechanisms. These include decreased leptin, a proinflammatory adipokine, but mechanistic ...

Adult-onset leukodystrophies and genetic leukoencephalopathies comprise a diverse group of neurodegenerative disorders of white matter with a wide age of onset and phenotypic spectrum. Patients with ...