Resurrection of ancient forms of CD4 reveals how retroviruses have placed selective pressure on this gene in apes, acting to propagate infection-resistant alleles.

This valuable study focuses on defining how the HSP70 chaperone system utilizes J-domain proteins to regulate the heat shock response-associated transcription factor HSF1. Using a combination of ...

Time-lapse analyses of millions of antibiotic-stressed Escherichia coli characterize the diverse single-cell dynamics of persister cells that depend on antibiotics, culture conditions, and ...

This important study provides insights into the role of maternal behavior in the learning and ontogeny of vocalization. It finds evidence that the maternal behavior of sac-winged bats (Saccopteryx ...

This fundamental study explores a novel cellular mechanism underlying the degeneration of locus coeruleus neurons during chronic restraint stress. The evidence supporting the overexpression of LC ...

Researchers have created a library of genetically engineered fruit flies linked to individual neurons in the nerve cord to characterise the circuits controlling wing motion.

Experiments in fruit fly larvae show that epidermal cells can communicate with sensory neurons to drive responses to pain.

This study presents a valuable meta-analysis that highlights low and highly variable breast cancer survival rates across Africa, emphasizing the pressing need for public health in Africa. The evidence ...

This study provides a valuable extension of credibility-based learning research by showing how feedback reliability can distort reward-learning biases in a disinformation-like bandit task. Although ...

The authors confirm that telomeres in telomerase-positive cells terminate with 5'-ATC in a Pot1-dependent manner, and demonstrate that this principle holds true in telomerase-negative ALT cells as ...

This valuable study uses consensus-independent component analysis to highlight transcriptional components (TC) in high-grade serous ovarian cancers (HGSOC). The study presents a convincing preliminary ...