CD8 T cell exhaustion is a key underlying factor limiting immunity in chronic infections and cancer. Persistent antigen exposure antagonizes formation of functional memory CD8 T cells that provide ...

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease lacking effective disease-modifying therapies. To better understand the mechanisms underlying motor neuron degeneration, we ...

Vaccination during the follicular phase of the menstrual cycle results in a higher chance of side effects, but a longer time to infection.