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生物通
6 天
Cell:尼帕病毒聚合酶复合物的结构和功能分析
现在,研究人员使用低温电子显微镜(cryo-EM)来阐明尼帕病毒聚合酶复合物(大蛋白和磷蛋白)的结构。不仅如此,他们还对聚合酶进行了结构、生物物理和深入的功能分析。 波士顿大学医学院病毒学、免疫学和微生物学教授Rachel Fearns博士说:“确定如何调节聚合酶来开启和关闭病毒复制所需的不同酶活性将会改变游戏规则,这项研究代表了朝着这一目标迈出的关键一步。” ...
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