Background Gastric cancer (GC) remains a major cause of cancer-related mortality, particularly in China, where delayed diagnosis contributes to poor outcomes. Current diagnostic approaches are limited ...

The goal of the HMS Initiative for RNA Medicine (HIRM) is to make and translate RNA discoveries into novel therapeutics and diagnostics by fostering a climate of outstanding basic, translational and ...

摘要：内侧颞叶癫痫（mesial temporal lobe epilepsy, mTLE）是局灶性癫痫的一个亚型，约三分之一患者发展为药物抵抗性癫痫，可能由包括结构改变和非编码RNA（non-coding RNA, ncRNA）失调在内的多种机制驱动。然而， 摘要：内侧颞叶癫痫（mesial temporal lobe epilepsy, mTLE）是局灶性癫痫的一个亚型，约三分之一患者发展为药 ...

The burden of cancer is grave, global, and continuing to grow. Researchers are working to develop new approaches and broaden the reach of existing modalities by bolstering traditional therapies, ...

Abstract: Pancreatic cancer is one of the most malignant cancers with rapid progression and poor prognosis. The use of transcriptional data can be effective in finding new biomarkers for pancreatic ...

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RNA-seq has represented a pivotal breakthrough in transcriptomics. Among the successful factors of this technology, two features have had the highest impact: the capability of measuring the whole ...

摘要：施万细胞（Schwann cells, SCs）在周围神经再生中发挥关键作用，损伤后经历从髓鞘形成表型向修复表型的动态转变。尽管SC来源细胞外囊泡（SC-EVs）被认为是神经修复过程中细胞间通讯的重要介质，其阶段特异性分子载荷及功能作用尚不完全清楚。本研 摘要：施万细胞（Schwann cells, SCs）在周围神经再生中发挥关键作用，损伤后经历从髓鞘形成表型向修复表型的动态转变。尽管SC ...

The “dark proteome” includes uncharacterized proteins that may influence cancer growth, immune evasion, and therapy ...

CellRanger uses its own "filtered" version of annotations (GTF file) which is a subset of ENSEMBL annotations, with several gene biotypes removed (mostly small non-coding RNA). Annotations affect the ...