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In vivo affinity maturation of antibodies involves mutation of hot spots in the DNA encoding the variable regions. We have used this information to develop a strategy to improve antibody affinity in ...

Laboratory for Drug Discovery in Neurodegeneration, Harvard NeuroDiscovery Center, Brigham and Women’s Hospital, Harvard Medical School, 65 Landsdowne Street, Fourth Floor, Cambridge, Massachusetts ...

E.T. the Extra-Terrestrial was a global phenomenon that spawned many knockoffs, with films like Purple People Eater, Badi, ...

Département de Pharmacologie-Physiologie, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke J1H 5N4, Québec, Canada Institut de Pharmacologie de Sherbrooke, ...

A recent wave of restaurant app launches, app relaunches, loyalty upgrades and app-centered promotions shows how quickly the role of the branded restaurant app is changing. For years, the basic ...

Brand moments are where luxury labels earn cultural credibility, but cultivating such equity is no small challenge.

Background Hepatocellular carcinoma (HCC), one of the most prevalent cancers worldwide, has a high mortality owing to diagnostic challenges and therapeutic resistance. Lactate metabolism and protein ...

Unlock the full InfoQ experience by logging in! Stay updated with your favorite authors and topics, engage with content, and download exclusive resources. Erik Steiger discusses the operational pain ...

1 Department of Human Physiology and Sports Medicine, Faculty of Physical Education and Physical Therapy, Vrije Universiteit Brussel, Brussels, Belgium 2 Center for Human Movement Sciences and ...