Exploration means looking around, observing, describing and mapping undiscovered territory, not testing theories or models. The goal is to discover things we neither knew or expected, and to see ...

Abstract: In the diagnosis and treatment of cancer, cancer classification is a vital issue. Gene selection is much needed to solve the high dimensionality issue in microarray data, small sample size, ...

Although there is only one human genome sequence, different genes are expressed in many different cell types and tissues, as well as in different developmental stages or diseases. The structure of ...

Abstract: In unsupervised learning literature, the study of clustering using microarray gene expression datasets has been extensively conducted with nonnegative matrix factorization (NMF), spectral ...

Background Wolf–Hirschhorn syndrome (WHS) is a contiguous gene deletion syndrome involving variable size deletions of the 4p16.3 region. Seizures are frequently, but not always, associated with WHS.

Genes that follow similar expression trajectories in response to stress or stimulus tend to share biological functions. Thus, it is reasonable and common to cluster genes by expression trajectories.

Scientists at ETH Zurich have identified a compound that sharply reduced nerve-cell death in mice engineered to develop ...

Colorectal cancer (CRC) remains one of the most heterogeneous malignancies, with substantial variability in molecular ...

After several examples of undisclosed alterations in reagent suppliers’ antibody catalogues surfaced, researchers call for transparency to rebuild trust.