A non-detect on a liquid biopsy is not a zero — it means the resistant clone is below the assay's limit of detection (LoD). At low VAF, detection flickers (finite-molecule Poisson sampling): detect, ...
Correspondence to Dr Christien Janneke van der Woude, Department of Gastroenterology and Hepatology, Erasmus MC-University Medical Center Rotterdam, 3015 CE Rotterdam, The Netherlands ; ...
aDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA bCenter for Vaccine Research and Pandemic Preparedness, Icahn School of Medicine at Mount Sinai, New York, NY, ...
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