The induced pluripotent stem cell (iPSC) technology has transformed in vitro research and holds great promise to advance regenerative medicine. iPSCs have the capacity for an almost unlimited ...

Paper in Cloning and Stem Cells shows that animal eggs do not support specific reprogramming toward the normal human embryonic state. Investigators at Advanced Cell Technology (ACTC) have found that ...

Human cellular reprogramming to induced pluripotency is still an inefficient process, which has hindered studying the role of critical intermediate stages. Here we take advantage of high efficiency ...

Human-induced pluripotent stem cells (hiPSCs) can differentiate into various tissues, an invaluable characteristic for personalized regenerative medicine, basic and translational research, and drug ...

Cellular reprogramming is the hottest topic in longevity science, with tech titans like Sam Altman investing in it. It's now being tested in humans.

A study published in the journal Stem Cells Reports reveals that a cellular reprogramming methodology allows the creation of neural networks that reproduce unique characteristics of human ...

Studies on diseases that affect the human brain are usually based on animal models which cannot reproduce the complexity of human neuropathies. Therefore, these methodologies often fail when applied ...

In a groundbreaking study published in Nature, Australian scientists have resolved a long-standing problem in regenerative medicine. Led by Professor Ryan Lister from the Harry Perkins Institute of ...

Human skin cells have been reprogrammed into heart valve cells and then used to successfully transplant a pig heart valve into a rodent, led by the research of a Northeastern University professor. The ...

Scientists have produced stem cells from the endangered Grévy's zebra using human reprogramming factors. Further comprehensive gene analyses identified key genes that are also found in human and mouse ...