The RNA world hypothesis proposes that early life was based on RNA, which subsequently devolved the storage of information to more stable DNA, and catalytic functions to more versatile proteins.

The goal of the HMS Initiative for RNA Medicine (HIRM) is to make and translate RNA discoveries into novel therapeutics and diagnostics by fostering a climate of outstanding basic, translational and ...

Background Gastric cancer (GC) remains a major cause of cancer-related mortality, particularly in China, where delayed diagnosis contributes to poor outcomes. Current diagnostic approaches are limited ...

Background and objective Gastric cancer (GC) remains a prevalent and preventable disease, yet accurate early diagnostic methods are lacking. Exosome non-coding RNAs (ncRNAs), a type of liquid biopsy, ...

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Esophageal cancer, which is cancer of the swallowing tube, has only a 22.2% five-year relative survival rate, but early ...

Citrus crops are among the world's most familiar fruits, but their genomes have remained difficult to interpret because of ...

Neurological disorders represent a growing global health challenge, yet the molecular mechanisms underlying their onset and progression remain incompletely ...

In cancer research, one person's junk is increasingly becoming another person's treasure. Scientists have uncovered new evidence showing how recently evolved "junk DNA" genetic elements can become ...

A study recently published in Current Molecular Pharmacology has uncovered a novel mechanism by which the long non‑coding RNA ...

Recent research suggests that long non coding RNAs, a type of genetic material that does not make proteins but helps control how genes work, may be important for keeping telomeres healthy. This ...

Abstract: Pancreatic cancer is one of the most malignant cancers with rapid progression and poor prognosis. The use of transcriptional data can be effective in finding new biomarkers for pancreatic ...