Improvement in IIM activity, as measured by the International Myositis Assessment and Clinical Studies Group (IMACS) definitions of improvement (DOI), may be more likely with abatacept treatment ...

Larger studies looking at the benefits and harms of anti-TNF compared with conventional treatment for children with active Crohn's disease are needed. Among the important outcomes to be included are ...

Due to a lack of robust evidence, we could not determine the benefits and unwanted effects of hospital networks (organised trauma systems) or individual hospitals (designated trauma centres) that are ...

We found nine studies involving a total of 689 women with stress urinary incontinence. Nine studies compared vaginal lasers to either sham or lubricant, and one study compared vaginal lasers to ...

- Corticosteroids may decrease transient inflammatory reaction events associated with antibiotic treatment of leptospirosis infection, although the certainty of this evidence is very uncertain.

Palivizumab, when given through the veins or into a muscle (systemically), reduces hospitalisations due to respiratory syncytial virus (RSV) and reduces respiratory problems later on (chest wheezing), ...

Transcranial laser therapy (low-level light therapy applied to the head) does not reduce the number of people who die or have moderate to severe disability at 90 days after ischaemic stroke (where ...

Why systematic and rigorous searches are important, planning and designing search strategies, sources of studies, managing and reporting the process.

Cochrane publishes high-quality health evidence to improve health for all. The World Health Organization, health professionals and people like you use our evidence to make informed choices about ...

Topical silver treatments and silver dressings are increasingly used for the local treatment of contaminated or infected wounds, however, there is a lack of clarity regarding the evidence for their ...

Cochrane Interactive Learning is our comprehensive course on how to conduct a systematic review. Equip yourself, or your staff and students, with the skills to conduct systematic reviews through ...

Dysmenorrhoea is a common gynaecological problem consisting of painful cramps accompanying menstruation, which in the absence of any underlying abnormality is known as primary dysmenorrhoea. Research ...