Monocytes are central to innate and adaptive immunity, regulating tissue homeostasis and inflammation. However, data on their ...

Introduction People diagnosed with tuberculosis (TB) after death (postmortem) experience the ultimate diagnostic delay. We ...

Correspondence to Professor David B Price, Academic Primary Care, University of Aberdeen, Aberdeen AB25 2ZD, UK; dprice{at}opri.sg Background Little is known about the impact of exacerbations on COPD ...

Airway-occluding mucus plugs (MPs)—as identified on CT scans—are frequent in patients with chronic obstructive pulmonary ...

Introduction International guidelines recommend a severity-based approach to management in community-acquired pneumonia. CURB65, CRB65 and the Pneumonia Severity Index (PSI) are the most widely ...

BACKGROUND Pulmonary rehabilitation programmes improve the health of patients disabled by lung disease but their cost effectiveness is unproved. We undertook a cost/utility analysis in conjunction ...

Background Non-invasive ventilation (NIV) is an effective form of treatment in patients with obesity hypoventilation syndrome (OHS) who have concomitant severe obstructive sleep apnoea (OSA). However, ...

4 The Nossal Institute for Global Health, The University of Melbourne, Melbourne, Victoria, Australia Background Pulmonary rehabilitation is a cornerstone of care for COPD but uptake of traditional ...

Background Malignant pleural effusion (MPE) causes debilitating breathlessness and predicting survival is challenging. This study aimed to obtain contemporary data on survival by underlying tumour ...

Background The prompt and precise diagnosis of active pulmonary tuberculosis (TB) is crucial for controlling this disease and ...

Rising hospital admissions due to respiratory disease (RD) are a major challenge to hospitals. This study explored modifiable social risk factors among 4478 older adults from the English Longitudinal ...

UK Centre for Tobacco Control Studies, Wolfson Institute of Preventive Medicine, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK Background A recent ...