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Alzheimer, Drugs and Systematic Reviews

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Scientific American · 17h
Effect of antiamyloid Alzheimer’s drugs ‘absent or trivial,’ Cochrane review finds
Drugs that were once hailed as possible breakthroughs in the battle to treat Alzheimer’s have no meaningful clinical effect on the disease’s progression, a new Cochrane review found.

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MedPage Today · 22h
Alzheimer's Drug Review Ignites Backlash From Experts
 · 1d
New Alzheimer's Drugs Provide No Meaningful Benefit, Major Evidence Review Concludes
 · 1d
Alzheimer's bombshell as meds 'make no difference' and 'cause bleeding'
Drugs claimed to slow the progression of Alzheimer's disease "make no meaningful difference to patients " while heightening the risk of swelling and bleeding in the brain, according to a new review.

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 · 1d
Effect of ‘gamechanger’ Alzheimer’s drugs ‘trivial’, review concludes
 · 1d
Finding drugs to slow dementia 'more difficult than establishing a colony on Mars'
 · 1d
Analysis of Alzheimer’s Drugs Stirs Debate About Their Effectiveness
The experts noted that data from the two most recent drugs studied — Leqembi and Kisunla — showed they could slow cognitive decline, which led to approval from the Food and Drug Administration and mad...

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 · 1d
Alzheimer’s bombshell as top scientists conclude - ‘the drugs don’t work’
 · 1d
Alzheimer drugs hailed as blockbuster dementia treatment do not work, review claims sparking row between scientists
8h

Study suggests some Alzheimer's symptoms may begin outside the brain

UCF researchers have uncovered evidence that some movement-related symptoms of Alzheimer's disease may originate outside the brain, which could change how the disease is diagnosed and treated in the future.
3don MSN

New Alzheimer’s research shows the disease affects men and women differently. What it could mean for testing and care

It’s “a move away from a one-size-fits-all framework for Alzheimer’s disease.”
2d

What’s the deal with Alzheimer’s disease and amyloid?

The retraction came from Neurobiology of Aging, which removed a 2011 paper claiming to show that a version of a protein called amyloid-β was responsible for memory loss in Alzheimer’s disease. On its own, that might not seem notable; bad papers can make it through peer review and are only caught after publication.
Neuroscience News
6h

Could Alzheimer’s Begin in the Nerves, Not the Brain?

Does Alzheimer’s start in the muscles? Research reveals that motor neuron mutations disrupt the neuromuscular junction independent of the brain.
1d

Much-hyped Alzheimer's drugs removed amyloid yet brought no meaningful gains over 18 months

Drugs once hailed as a breakthrough in the fight against Alzheimer's disease do not meaningfully help patients, a major review found Thursday, however some experts criticized the research.
4h

Common condition raises your risk of dementia by 66%

New findings show that a condition that affects 10% of US adults over 65 is likely increasing their risk of dementia by more than half. The good news, though, is that the condition is mostly treatable.
10h

6 Common Medications That May Lower Your Dementia Risk

Diabetes is associated with an increased risk of dementia, and a few drugs for Type 2 diabetes, including metformin and a class of medication called sodium-glucose cotransporter 2 (SGLT2) inhibitors, appear to modestly lower that risk, though some studies don’t show an effect.
3d

Bill Gates isn't backing 'Brain Honey,' other alleged Alzheimer's remedies. They're scams

Gates is a supporter of Alzheimer’s research, but scammers are using his name and likeness to promote fraudulent “cures” for the disease.
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